Motif ID: TAL1_TCF{3,4,12}.p2

Z-value: 0.736


Transcription factors associated with TAL1_TCF{3,4,12}.p2:

Gene SymbolEntrez IDGene Name
TAL1 6886 T-cell acute lymphocytic leukemia 1
TCF12 6938 transcription factor 12
TCF3 6929 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF3chr19_-_16012460.448.6e-02Click!
TCF12chr15_+_54998115-0.351.8e-01Click!
TCF4chr18_-_51406841-0.263.3e-01Click!
TAL1chr1_-_47468029-0.194.8e-01Click!


Activity profile for motif TAL1_TCF{3,4,12}.p2.

activity profile for motif TAL1_TCF{3,4,12}.p2


Sorted Z-values histogram for motif TAL1_TCF{3,4,12}.p2

Sorted Z-values for motif TAL1_TCF{3,4,12}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TAL1_TCF{3,4,12}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_149004852 0.858 CTSS
cathepsin S
chr2_-_158008763 0.769 NM_004288
CYTIP
cytohesin 1 interacting protein
chr11_+_5367182 0.676 NM_001004756
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr17_+_38256710 0.667 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr1_-_149004879 0.663 CTSS
cathepsin S
chr5_-_176258920 0.647 NM_002115
HK3
hexokinase 3 (white cell)
chr2_-_154043403 0.619 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr11_-_56166490 0.615 NM_001002925
OR5AP2
olfactory receptor, family 5, subfamily AP, member 2
chr9_-_106420305 0.593 NM_001001956
OR13C9
olfactory receptor, family 13, subfamily C, member 9
chr22_+_38652555 0.588 GRAP2
GRB2-related adaptor protein 2
chr1_+_246718487 0.527 NM_001004697
OR2T5
olfactory receptor, family 2, subfamily T, member 5
chr10_-_73518772 0.510 NM_001134434
NM_014767
SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chr17_+_40594046 0.507 NM_144608
HEXIM2
hexamthylene bis-acetamide inducible 2
chr1_+_32489426 0.503 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr10_-_14090459 0.499 FRMD4A
FERM domain containing 4A
chr13_-_85271329 0.483 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr1_-_156800017 0.445 NM_001160325
OR6P1
olfactory receptor, family 6, subfamily P, member 1
chr4_-_20594645 0.434 KCNIP4
Kv channel interacting protein 4
chr22_+_22907443 0.424 NM_019601
SUSD2
sushi domain containing 2
chr17_-_53761119 0.420 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr19_+_15699833 0.409 NM_013939
OR10H2
olfactory receptor, family 10, subfamily H, member 2
chr1_-_158948176 0.407 NM_001778
CD48
CD48 molecule
chr10_-_49792282 0.396 NM_001006939
LRRC18
leucine rich repeat containing 18
chr12_+_63510481 0.383


chr2_-_233586164 0.379 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr5_-_131907071 0.377 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr8_-_81155564 0.368 NM_001025252
TPD52
tumor protein D52
chr19_+_15765760 0.344 NM_001004466
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr1_-_246789396 0.334 NM_001004694
OR2T29
OR2T5
olfactory receptor, family 2, subfamily T, member 29
olfactory receptor, family 2, subfamily T, member 5
chr5_+_14493905 0.330 TRIO
triple functional domain (PTPRF interacting)
chr5_+_167651063 0.330 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chrX_+_128741562 0.328 NM_018990
SASH3
SAM and SH3 domain containing 3
chr17_+_38256886 0.320


chr17_-_9863929 0.317 GAS7
growth arrest-specific 7
chr10_+_85923473 0.311 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr6_-_163068788 0.304 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr12_-_101835026 0.300 PAH
phenylalanine hydroxylase
chr2_+_46560207 0.294 NM_001145051
LOC388946
transmembrane protein ENSP00000343375
chr6_-_41811916 0.291 NM_001167827
TFEB
transcription factor EB
chr7_+_94953148 0.288 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr6_-_29431950 0.275 NM_030876
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr17_+_36642240 0.273 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr3_+_196933481 0.272 MUC20
mucin 20, cell surface associated
chr19_-_44060729 0.271 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr2_+_191009265 0.266 MFSD6
major facilitator superfamily domain containing 6
chr14_-_93493519 0.265 NM_016150
ASB2
ankyrin repeat and SOCS box containing 2
chr6_-_30188845 0.255 NM_007028
TRIM31
tripartite motif containing 31
chr5_+_173405343 0.252 HMP19
HMP19 protein
chr7_+_75977680 0.252 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr1_-_156635879 0.250 NM_001004475
OR10T2
olfactory receptor, family 10, subfamily T, member 2
chrX_+_102918409 0.248 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr11_-_62445308 0.247 CHRM1
cholinergic receptor, muscarinic 1
chr18_+_19826734 0.244 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr11_-_66431910 0.243 NM_022172
PC
pyruvate carboxylase
chr7_-_36992221 0.238 NM_130442
ELMO1
engulfment and cell motility 1
chrX_+_38096679 0.235 NM_000531
OTC
ornithine carbamoyltransferase
chr19_-_14853166 0.231 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr11_-_62445587 0.230 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr5_+_173405298 0.230 NM_015980
HMP19
HMP19 protein
chr6_-_56515640 0.229


chrX_-_46503540 0.227 SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr11_-_71424614 0.225


chr20_+_36643251 0.221 NM_001018082
ADIG
adipogenin
chr17_+_45617676 0.220


chr14_+_19513442 0.216 NM_001005486
OR4K15
olfactory receptor, family 4, subfamily K, member 15
chr17_-_46479127 0.216 SPAG9
sperm associated antigen 9
chr4_-_185921384 0.213 ACSL1
acyl-CoA synthetase long-chain family member 1
chr2_-_96320185 0.212 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr11_+_5558682 0.209 NM_001005162
OR52B6
olfactory receptor, family 52, subfamily B, member 6
chr16_+_4546491 0.209 NM_001145011
LOC342346
hypothetical protein LOC342346
chr22_+_22907417 0.207 SUSD2
sushi domain containing 2
chr9_+_114376709 0.206 KIAA1958
KIAA1958
chr8_-_20084892 0.206 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chrX_+_85404626 0.203 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chrX_+_128741578 0.198 SASH3
SAM and SH3 domain containing 3
chrX_+_102918453 0.197 PLP1
proteolipid protein 1
chr9_-_135435165 0.196 NM_001080515
FAM163B
family with sequence similarity 163, member B
chr10_-_105410840 0.196


chrX_+_46967360 0.195 NM_001170460
CDK16
cyclin-dependent kinase 16
chr16_-_79811475 0.194 NM_001076780
NM_052892
PKD1L2

polycystic kidney disease 1-like 2

chr6_-_33028790 0.189 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chrX_-_110400406 0.186 NM_014289
CAPN6
calpain 6
chr10_-_50012058 0.185 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr19_-_38052481 0.184 NM_001126335
NM_014270
SLC7A9

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

chr2_-_233586145 0.181 NGEF
neuronal guanine nucleotide exchange factor
chr2_+_68445821 0.178 NM_002664
PLEK
pleckstrin
chr1_-_92724181 0.175 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr5_-_134810696 0.169 NM_130848
C5orf20
chromosome 5 open reading frame 20
chr22_+_23309717 0.169 NM_013430
GGT1
gamma-glutamyltransferase 1
chr5_+_134331494 0.169 NM_178019
CATSPER3
cation channel, sperm associated 3
chr22_-_14829803 0.166 NM_001005239
OR11H1
olfactory receptor, family 11, subfamily H, member 1
chrX_+_102918089 0.161 NM_001128834
PLP1
proteolipid protein 1
chr17_+_72827227 0.160 SEPT9
septin 9
chr12_-_8110268 0.155 C3AR1
complement component 3a receptor 1
chr17_-_16816113 0.153 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr9_+_12764988 0.151 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr22_-_41672990 0.150 NM_007229
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr1_-_169888373 0.150 NM_000261
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr12_-_7153068 0.148 NM_016546
C1RL
complement component 1, r subcomponent-like
chrX_-_15593074 0.147 NM_020665
TMEM27
transmembrane protein 27
chr22_+_34979118 0.141 APOL1
apolipoprotein L, 1
chr19_+_17499064 0.140 FAM129C
family with sequence similarity 129, member C
chr8_-_11966664 0.139 NM_001195257
NM_001037804
LOC100133267
DEFB130
defensin, beta 130-like
defensin, beta 130
chr10_+_71482362 0.138 NM_018649
H2AFY2
H2A histone family, member Y2
chr4_+_69465107 0.138 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chrX_+_125781427 0.137 NM_001122716
CXorf64
chromosome X open reading frame 64
chr16_+_11966464 0.136 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_+_242283129 0.136 NM_006352
ZNF238
zinc finger protein 238
chr2_-_97775300 0.136 TMEM131
transmembrane protein 131
chr17_-_9864048 0.134 GAS7
growth arrest-specific 7
chr19_+_18069596 0.134 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr14_-_20179689 0.133 NM_001001968
OR6S1
olfactory receptor, family 6, subfamily S, member 1
chr22_-_34886727 0.132 NM_145640
APOL3
apolipoprotein L, 3
chr12_-_101835510 0.128 NM_000277
PAH
phenylalanine hydroxylase
chr3_+_35697432 0.123 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_-_149004916 0.122 NM_004079
CTSS
cathepsin S
chr2_-_25320582 0.122 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr6_-_163068749 0.121 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr6_-_169392771 0.120


chr10_-_105427898 0.119 SH3PXD2A
SH3 and PX domains 2A
chr17_+_71141108 0.119 NM_001162995
LOC643008
hypothetical protein LOC643008
chr13_-_26232777 0.118 NM_005288
GPR12
G protein-coupled receptor 12
chr6_+_29249289 0.118 NM_030905
OR2J2
olfactory receptor, family 2, subfamily J, member 2
chr10_+_11246934 0.118 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr1_-_9052207 0.118 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr16_+_66836798 0.117 PLA2G15
phospholipase A2, group XV
chr16_-_70168449 0.117 NM_000353
TAT
tyrosine aminotransferase
chr17_+_19255083 0.116 NM_007148
RNF112
ring finger protein 112
chr19_+_56452775 0.115 NM_173635
C19orf75
chromosome 19 open reading frame 75
chr17_+_35372751 0.114 NM_178171
GSDMA
gasdermin A
chr12_-_8110196 0.114 NM_004054
C3AR1
complement component 3a receptor 1
chr1_+_246703249 0.114 NM_001005495
OR2T3
olfactory receptor, family 2, subfamily T, member 3
chr6_-_163068790 0.113 NM_004562
NM_013987
NM_013988
PARK2


parkinson protein 2, E3 ubiquitin protein ligase (parkin)


chr11_-_57752923 0.112 NM_001004471
OR10Q1
olfactory receptor, family 10, subfamily Q, member 1
chr10_-_121286034 0.112 NM_002925
RGS10
regulator of G-protein signaling 10
chrX_-_46503415 0.111 NM_032591
SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr1_+_245835478 0.111 NM_001001914
OR2G3
olfactory receptor, family 2, subfamily G, member 3
chr19_-_11549441 0.111 ACP5
acid phosphatase 5, tartrate resistant
chr12_-_14024187 0.110 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr19_-_11549484 0.109 ACP5
acid phosphatase 5, tartrate resistant
chrX_-_47941142 0.108 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr1_-_23393808 0.108 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr7_+_155129943 0.106 NM_053043
RBM33
RNA binding motif protein 33
chr11_-_58368555 0.106 NM_145016
GLYATL2
glycine-N-acyltransferase-like 2
chr11_-_74478405 0.105 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr7_+_31693155 0.105 NM_001145123
NM_006658
C7orf16

chromosome 7 open reading frame 16

chr7_+_113853790 0.103 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr12_-_2814410 0.102 NM_031474
NRIP2
nuclear receptor interacting protein 2
chr9_+_115303527 0.101 NM_130795
RGS3
regulator of G-protein signaling 3
chr17_+_36515166 0.101 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr3_-_129668780 0.101 NM_153330
DNAJB8
DnaJ (Hsp40) homolog, subfamily B, member 8
chr11_-_55460451 0.101 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr17_+_44642587 0.098 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr11_-_4902144 0.096 NM_001005237
OR51G1
olfactory receptor, family 51, subfamily G, member 1
chr3_+_49019498 0.096 NM_018031
WDR6
WD repeat domain 6
chr14_+_38804226 0.096 NM_203354
CTAGE5
CTAGE family, member 5
chr22_+_34979062 0.095 NM_001136540
NM_001136541
NM_003661
NM_145343
APOL1



apolipoprotein L, 1



chr2_-_240618518 0.095 NM_001005853
OR6B2
olfactory receptor, family 6, subfamily B, member 2
chr4_+_54790020 0.095 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr12_+_122510338 0.095 NM_180699
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr13_+_107719977 0.094 NM_001145645
NM_006573
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr2_-_25320299 0.093 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_+_116181927 0.092 NHLH2
nescient helix loop helix 2
chr11_-_65182411 0.091 RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chrX_-_111809929 0.090 NM_178175
LHFPL1
lipoma HMGIC fusion partner-like 1
chr7_+_155130086 0.090 RBM33
RNA binding motif protein 33
chr15_-_40236061 0.090 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr6_+_167456230 0.089 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chrX_-_19598912 0.089 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr2_+_232165818 0.089 NM_152614
C2orf57
chromosome 2 open reading frame 57
chrX_-_110400321 0.089 CAPN6
calpain 6
chr5_-_142764295 0.088 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr8_-_86441115 0.087 NM_001164830
CA1
carbonic anhydrase I
chr6_+_126282078 0.087 NCOA7
nuclear receptor coactivator 7
chrX_+_48127911 0.087 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chr7_+_149104063 0.087 NM_198455
SSPO
SCO-spondin homolog (Bos taurus)
chr16_+_2528022 0.086 PDPK1
3-phosphoinositide dependent protein kinase-1
chr22_-_38258716 0.084 NM_194326
RPS19BP1
ribosomal protein S19 binding protein 1
chr6_-_30236667 0.084 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr19_-_11549508 0.082 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr20_-_3635774 0.081 NM_023068
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr7_+_155129904 0.079 RBM33
RNA binding motif protein 33
chrX_+_41191630 0.079 NM_022567
NYX
nyctalopin
chr19_-_4289750 0.078 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr12_-_101835183 0.078 PAH
phenylalanine hydroxylase
chr10_+_7785347 0.077 ITIH2
inter-alpha (globulin) inhibitor H2
chr2_-_225519974 0.077 DOCK10
dedicator of cytokinesis 10
chr21_-_44506526 0.077 NM_013369
NM_175867
DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

chr3_-_197726587 0.077 NM_001077657
C3orf43
chromosome 3 open reading frame 43
chr17_-_1037312 0.076 NM_001159746
ABR
active BCR-related gene
chr12_+_118590039 0.075 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr11_+_65164167 0.075 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr5_-_180560535 0.074 NM_203297
TRIM7
tripartite motif containing 7
chr11_-_56914668 0.074 NM_002728
PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr6_-_41811323 0.074 TFEB
transcription factor EB
chr6_-_41230003 0.073 NM_178174
TREML1
triggering receptor expressed on myeloid cells-like 1
chr12_+_55674496 0.073 NM_007264
GPR182
G protein-coupled receptor 182
chr19_+_2340768 0.073 NM_182973
TMPRSS9
transmembrane protease, serine 9
chr12_+_50568010 0.073 NM_001130015
NM_182608
ANKRD33

ankyrin repeat domain 33

chr15_+_79276273 0.073 NM_001172128
IL16
interleukin 16 (lymphocyte chemoattractant factor)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.50 9.05e-12 GO:0007608 sensory perception of smell
4.24 1.27e-11 GO:0007606 sensory perception of chemical stimulus
2.81 2.80e-07 GO:0007600 sensory perception
2.28 1.18e-06 GO:0050877 neurological system process
1.95 1.49e-04 GO:0003008 system process
1.35 3.24e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.41 3.95e-03 GO:0071944 cell periphery
1.40 5.46e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.72 4.31e-13 GO:0004984 olfactory receptor activity
2.94 1.69e-09 GO:0004930 G-protein coupled receptor activity
2.33 1.52e-07 GO:0004888 transmembrane receptor activity
1.99 7.03e-06 GO:0004872 receptor activity
1.77 1.68e-04 GO:0004871 signal transducer activity
1.77 1.68e-04 GO:0060089 molecular transducer activity